Cover of 1997 Supplement 2, EHP EHP Supplement

Volume 105 Supplement 2, March 1997

Experimental Approaches to Chemical Sensitivity


Table of Contents

Overview
Introduction and Overview
Howard Kipen and Nancy Fiedler
Chemical Sensitivity: The Scientific Literature
Nancy Fiedler and Howard Kipen
Clinical Perspectives
Profile of Patients with Chemical Injury and Sensitivity
Grace Ziem and James McTamney
Clinical Characteristics of Chemical Sensitivity: An Illustrative Case History of Asthma and MCS
Gerald H. Ross
Commentary: Laboratory Testing of the Patient with Multiple Chemical Sensitivity
Howard R. Kehrl
Theoretical Perspectives
Toxicant-induced Loss of Tolerance--An Emerging Theory of Disease?
Claudia S. Miller
Commentary: Evolving Concepts of Chemical Sensitivity
Robert C. MacPhail
Individual Differences in Neural Sensitization and the Role of Context in Illness from Low-level Environmental Chemical Exposures
Iris R. Bell, Gary E. Schwartz, Carol M. Baldwin, Elizabeth E. Hardin, Nancy G. Klimas, John P. Kline, Roberto Patarca, and Zhi-Ying Song
Potential Role of Stress and Sensitization in the Development and Expression of Multiple Chemical Sensitivity
Barbara A. Sorg and Balakrishna M. Prasad
Hypothesis for Induction and Propagation of Chemical Sensitivity Based on Biopsy Studies
William J. Meggs
Psychophysiological Hypotheses Regarding Multiple Chemical Sensitivity Syndrome
Paul M. Lehrer
Commentary: Systematic Considerations in the Area of Multiple Chemical Sensitivity
Vernon A. Benignus
Experimental Methods
Experimental Strategies for Research on Multiple Chemical Sensitivity
Bernard Weiss
Cognitive and Psychomotor Performance Tests and Experiment Design in Multiple Chemical Sensitivity
Anthony Wetherell
A Behavior-Genetic Approach to Multiple Chemical Sensitivity
David B. Newlin
Human Drug Discrimination and Multiple Chemical Sensitivity: Caffeine Exposure as an Experimental Model
Thomas Eissenberg and Roland R. Griffiths
Working Group Reports
Empirical Approaches for the Investigation of Toxicant-induced Loss of Tolerance
Claudia Miller, Nicholas Ashford, Richard Doty, Mary Lamielle, David Otto, Alice Rahill, and Lance Wallace
Pavlovian Conditioning and Multiple Chemical Sensitivity
Shepard Siegel and Richard Kreutzer
Psychoneuroimmunology
Nicholas Cohen, Howard Kehrl, Birgitta Berglund, Ann O'Leary, Gerald Ross, James Seltzer, and Clifford Weisel
Neurogenic Inflammation: With Additional Discussion of Central and Perceptual Integration of Nonneurogenic Inflammation
Rebecca Bascom, William J. Meggs, Mark Frampton, Kenneth Hudnell, Kaye Killburn, Gerd Kobal, Michelle Medinsky, and William Rea
Testing the Neural Sensitization and Kindling Hypothesis for Illness from Low Levels of Environmental Chemicals
Iris R. Bell, John Rossi III, Mary E. Gilbert, Gerd Kobal, Lisa A. Morrow, David B. Newlin, Barbara A. Sorg, and Ronald W. Wood

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Last update: March 27, 1997


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