Chemical Name:

Isopropanol

Formula:

(CH₃)₂CHOH

CAS #:

67-63-5

Synonyms:

Isopropyl Alcohol; Dimethylcarbinol; 2-Hydroxypropane; Propan-2-ol; 2-Propanol; Sec-Propyl Alcohol; Alcojel; Alcosolve; Avantin; Avantine; Chromar; Combi-Schutz; Hartosol; Imsol A; Isohol; Lutosol; Petrohol; Pro; n-Propan-2-ol; Propol; 2-Propyl Alcohol; Spectrar; Sterisol Hand Disinfectant; Takineocol; Alcosolve 2

Exposure Limits:

TLV: 400 ppm; 983 mg/m³ (as TWA); 500 ppm; 1230 mg/m³ (as STEL) (ACGIH 1991-1992).
OSHA PEL: TWA 400 ppm (980 mg/m³)
NIOSH REL: TWA 400 ppm (980 mg/m³) ST 500 ppm (1225 mg/m³)
NIOSH IDLH: 2000 ppm LEL

Uses:

This compound is used as a solvent in perfumery and cosmetics, in the preservation of pathological specimens and dehydration of tissues, as a non-aqueous moistening agent for tablet granulation, in hair preparations, in lotions, in liniments, as a solvent for creosote, resins, gums, inks, oils, lotions, shellac and essential oils, as an antifreeze mixture and as an extraction solvent in food preparation.  It is externally substituted for industrial methylated spirit and surgical spirit.  It is also used in the extraction of alkaloids, in quick-drying oils, in quick-drying inks, in the denaturing of ethyl alcohol, in body rubs, in after-shave lotions, in the manufacture of acetone, glycerol and isopropyl acetate; as a pharmaceutic aid (solvent), as an antiseptic, as a rubefacient, as a deicing agent for liquid fuels, as a dehydrating agent, as a window cleaner, in permanent hair wave preparations, in dye solutions, as a disinfectant and in pliable ice packs.

Some products that might contain Isopropanol include:

Cleaning products; personal care products; dyes; disinfectants; inks; fragrances; cosmetics; anti-freeze products

Routes of Exposure:

The substance can be absorbed into the body by inhalation of its vapor, by inhalation of its aerosol and by ingestion.

Symptoms of exposure:

Irritation of the skin, eyes, nose, throat and respiratory tract, dizziness, nausea, central nervous system depression, dizziness, giddiness and headache.  It can cause flushing, decrease in pulse rate, lowered blood pressure, anesthesia, narcosis, mental depression, hallucinations, distorted perceptions, dyspnea, respiratory depression, vomiting, corneal burns, eye damage and coma. It can also cause abdominal pain, hematemesis, and areflexia, oliguria followed by diuresis, generalized tenderness, induration and edema of muscles.  Prolonged skin con-tact may cause corrosion.  Drunkenness may also occur.

Target organs:

Eyes, skin, respiratory system

Inhalation risk:

A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.

Effects of short-term exposure:

The substance irritates the eyes, the skin and the respiratory tract. The substance may cause effects on the central nervous system, resulting in depression. Exposure far above the OEL may result in unconsciousness. The effects may be delayed. Medical observation is indicated.

Effects of long-term or repeated exposure:

Repeated or prolonged contact with skin may cause dermatitis

Special Warnings:

SAX TOXICITY EVALUATION: THR: Poison by ingestion and subcutaneous routes.  Moderately toxic to humans by an unspecified route.  Moderately toxic experimentally by intravenous and intraperitoneal routes.  Mildly toxic by skin contact.  Human systemic effects by ingestion or inhalation.  Experimental teratogenic and reproductive effects.  Mutagenic data.  An eye and skin irritant.